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Advancing Discovery

A paradigm shift in the translation to GMP manufacturing. We are raising the bar in biologics development services.

The Wheeler Difference

Wheeler Bio Speeds Up and Simplifies the Discovery-to-IND Process.

Wheeler Bio brings biologics drug innovators, discovery CROs, and CDMOs together to solve an outdated industry bottleneck with a unique partnering model, built on shared success and lasting collaborations. The typical momentum drop between discovery and development poses significant challenges for emerging biopharma companies adding technical, financial, and regulatory risks. We believe these lifecycle challenges can be reduced with more democratization of manufacturing platforms.

Wheeler is proud to currently offer best-in class mammalian cell line development, GLP material supply, and an efficient path to GMP. Connect with our team today to learn more about how Wheeler can add value to your project.

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Get to IND Faster with Portable CMC™

With Portable CMC™, Wheeler is simplifying the connection between drug discovery and clinical manufacturing by standardizing and democratizing the innovation-to-impact process. A new bridge for translating discoveries to IND filing, innovators benefit from increased momentum during technology transfer and shorter timelines.

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Oklahoma City Headquarters

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Boston R&D Center

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CAR-TCR

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Wheeler Bio Integrates the Solentim® Ecosystem by Advanced Instrument...

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Wheeler 360⁰ Tour: Process Development Upstream

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Applying an Advanced Pharma 4.0 Perspective to Design the Facility of ...

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Reducing Time to IND, Increasing Quality, and Building Trust Through S...

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Wheeler Bio Announces $14M Seed Round To Expand Access To Portable CMC...

A Biomanufacturing Ecosystem

Oklahoma

Massachusetts

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Wheeler Headquarters

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Photograph of Wheeler's Boston facility for molecular biology, transient protein expression and cell line development/engineering

Boston R&D Center

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  • a checkmark graphic, used to indicate the capabilities of Wheeler and its equipment at its cell line development facility in Boston
    Transient Protein Production
  • a checkmark graphic, used to indicate the capabilities of Wheeler and its equipment at its cell line development facility in Boston
    Stable Cell Line Development
  • a checkmark graphic, used to indicate the capabilities of Wheeler and its equipment at its cell line development facility in Boston
    Preclinical Material Supply & Testing from Stable Pools
  • a checkmark graphic, used to indicate the capabilities of Wheeler and its equipment at its cell line development facility in Boston
    Process Development & Optimization
  • a checkmark graphic, used to indicate the capabilities of Wheeler and its equipment at its cell line development facility in Boston
    Process Characterization
  • a checkmark graphic, used to indicate the capabilities of Wheeler and its equipment at its cell line development facility in Boston
    Analytical Development & Qualifications
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    Formulation Development
  • a checkmark graphic, used to indicate the capabilities of Wheeler and its equipment at its cell line development facility in Boston
    Preclinical Material Supply & Testing from Stable Clones
  • a checkmark graphic, used to indicate the capabilities of Wheeler and its equipment at its cell line development facility in Boston
    GMP Drug Substance Manufacturing (Coming in Spring 2023)
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    Molecular Biology
  • a checkmark graphic, used to indicate the capabilities of Wheeler and its equipment at its cell line development facility in Boston
    Transient Protein Production
  • a checkmark graphic, used to indicate the capabilities of Wheeler and its equipment at its cell line development facility in Boston
    Preclinical Material Supply & Testing from Stable Pools
  • a checkmark graphic, used to indicate the capabilities of Wheeler and its equipment at its cell line development facility in Boston
    Advanced Cell Line Engineering
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Proven Successes

“Working with Wheeler’s team of consummate professionals has enabled us to accelerate our development, enabling us to file our PIND and IND within a year. We have accomplished so much in such little time due to Wheeler’s knowledge, expertise, and constant engagement with our process. We look forward to partnering with Wheeler for many years to come.”

John B. Mumm Ph.D.

President & CEO at Deka Biosciences

“Wheeler’s team of process and analytical development experts have been very responsive to our needs in securing critical data for the scale-up of seviprotimut-L for our pivotal, Phase 3 confirmatory trial. Their attention to detail, rigorous scientific approach and collaborative nature has been well received by the Polynoma CMC team.”

Patrick J. Mallon

COO at Polynoma

“It’s been extremely valuable to be able to remain comfortably within the 82VS partner network and engage in early problem-solving discussions with world-class professionals as experienced as those at Wheeler Bio. We've had extremely fruitful discussions about stage-appropriate development solutions that can support the translation of our discovery pipeline into scalable processes and it has been and continues to be a pleasure engaging with the collaborative team at Wheeler.”

Andrew Peterson, Ph.D.

CEO at Broadwing Bio

“You have an awesome team!”

John Conner

CMO at Deka Biosciences

“Just wanted you to know what a wonderful experience I have had with Wheeler. Everyone answers the phone, answers my million questions and is so nice and professional! It was like in the old days – lol! Great job!”

Crystal Sanjenis

Wheeler Covid Lab customer

“We have been working with the Wheeler team for about a year now and it has been a great experience. They are extremely knowledgeable and have been helpful to our entire team.”

Samantha Conner

Vice President of Program Management at Deka Biosciences

Push Boundaries. Affect Change.

We are a growing team of drug development professionals who share a passion for speed to clinical impact through collaboration.

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