Portable CMC®
CRO Partnerships
Provide your customers with a clearer, shorter, sightline to IND filing
Portable CMC® can be integrated with your CRO’s discovery processes. Wheeler puts its people, process and equipment inside your facility to extend its capabilities — giving your customers access to a state-of-the-art CMC development platform. Wheeler’s partnering approach democratizes access to standard drug substance processes for the benefit of all while adding real value to your company’s bottom line.
Partnering with Wheeler Bio is a competitive advantage:
- Access to Wheeler’s analytical, cell line development, process development and GMP expertise
- Access to drug substance manufacturing technology
- Add to existing offerings, without investing in manufacturing capacity
- Significantly derisk programs for customers and share in the benefits
PHASE™ - Wheeler Bio’s premier service experience for Alloy partners
Wheeler’s PHASE™ is a premier service experience offering a seamless transition from discovery to CMC for existing and future ATX-Gx platform users and Alloy Discovery Service partners.
PHASE™ integrates the antibody discovery process with our Portable CMC® platform to reduce the timeline from drug candidate selection to initiation of cell line development, resulting in significant risk reduction, increased manufacturing predictability, elimination of the RFP process, and improved knowledge transfer between the CRO and CDMO. Alloy partners that continue with our PHASE™ service also receive economic incentives for the most efficient use of CMC capital. Ultimately, PHASE™ aligns the ecosystem between drug developers, Alloy, and Wheeler to accelerate the translation of drug discoveries to clinical manufacturing.
Alloy partners that continue with our PHASE™ service also receive economic incentives for the most efficient use of CMC capital. Ultimately, PHASE™ aligns the ecosystem between drug developers, Alloy, and Wheeler to accelerate the translation of drug discoveries to clinical manufacturing.
With PHASE™, Alloy customers contracting Wheeler Portable CMC® Lead to Tox or Lead to Clinic services benefit from:
- Dollar-for-dollar reductions in Alloy commercial milestones for Wheeler services contracted
- Free CMC consulting to guide you from discovery to CMC development
- Zero-charge CHO pool generation for up to 4 leads
Additionally, Alloy customers contracting Wheeler Portable CMC® Lead to Clinic programs benefit from:
- A 50% reduction in the Wheeler initial payment
- Zero reservation fee required to hold manufacturing slots
This strategic integrated offering promises to significantly reduce risk, increase predictability, and boost your journey from discovery to successful clinical development, ultimately advancing your drug programs into the hands of patients more rapidly than ever before.